Our Vice Mexico team went to the Sonora desert in search of the Bufo Alvarius, an endemic toad species that contains a very high dosage of 5-MEO-DMT in it´s body. 5-MEO-DMT is said to be the most potent hallucinogenic in the world. Our guide through this trip was Octavio Rettig, a doctor who has studied this toad for more than eight year and has brought the medicine – as he calls the substance – all over the world. We went to Punta Chueca, Sonora, where we hanged out with the indigenous community who has been taking 5-MEO-DMT from the toad since pre-hispanic times. We met Grandpa Pancho – one of the elders of the town – and travelled with him to the sacred island of Isla Tiburón. There we had a small ceremony where we tried the substance for the very first time.